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Ambien is the brand name medication that contains zolpidem as an active ingredient. It is an oral medicine primarily useful in treating sleep problems. According to the guidelines, people can use Ambien only after try counseling and behavioral therapies. It helps fall asleep within 15 minutes of administration and keep the person stay asleep at larger doses. You can buy Ambien online in dosage formulations of oral tablets, sublingual tablets, and oral spray.
Ambien is a non-benzodiazepine drug that acts as a sedative and a hypnotic. It is a GABAA receptor agonist of the imidazopyridine class of drugs. Ambien works by increasing the effects of GABA neurotransmitters in the central nervous system and binds to the GABAA receptors the same as benzodiazepines do. It has a half-life of about 2-3 hours. However, this increases in patients with hepatic impairment.
Zolpidem, the primary ingredient of Ambien, got approval for medical use in the year 1992 in the United States. It is available both a brand and a generic version. Ambien is one of the most common prescriptions for sleep disorders, with more than 10 million prescriptions per year in the country.
Licit Uses :
Ambien is helpful for the management of short-term (usually 2-6 weeks) treatment of insomnia. People should administer the medication at the lowest possible dose. It is useful in improving sleep onset and helps to stay asleep for longer.
The American College of Physicians guidelines recommends Ambien for insomnia only as a second-line treatment after using non-pharmacological treatment options such as behavior therapy and cognitive therapy. It is the basis of a review conducted in 2012 that demonstrates the effectiveness of Ambien is more due to psychological effects.
For middle-night awakenings, give a low-dose formulation, which is 3.5 mg for men and 1.75 mg for women. Take it only when there are at least 4 hours between the time of administration and wake up.
Illicit Uses :
Ambien is a sedative-hypnotic and a less addictive alternative of Xanax for treating acute insomnia. It generally takes longer for a user to develop an addiction for Ambien than for Xanax. However, Ambien is still an addictive medication. It has a similar potential for abuse like benzodiazepines.
Ambien produces a strong sedative effect and thus a common drug of abuse. People generally do not use it recreationally. However, many users abuse it for the effects of euphoria and hallucinations.
Ambien contains the active ingredient zolpidem tartrate in the strengths of 5 mg and 10 mg.
The inactive ingredients of Ambien tablets are microcrystalline cellulose, magnesium stearate, hydroxypropyl methylcellulose, sodium starch glycolate, polyethylene glycol, lactose, and titanium dioxide. Additionally, the tablets also contain FDA approved color additives FD & C Red No. 40, polysorbate 80, and iron oxide colorant.
Ambien has zolpidem, which is a ligand of high-affinity positive modular of GABAA receptors. It enhances inhibition of GABAergic neurotransmission in the central nervous system. Ambien selectively binds to the pentameric ion channel of alpha1 subunits.
Ambien also has strong hypnotic properties and weak anticonvulsant, anxiolytic, and myorelaxant properties. It can bind the binary alpha-beta GABA receptors, where it shows to attach to the alpha1-alpha1 subunit interface.
Ambien may increase slow-wave sleep but causes no effect on stage 2 sleep. A meta-analysis comparing the effects of benzodiazepines with non-benzodiazepines shows a few consistent differences between Ambien and benzodiazepines in terms of total sleep duration, sleep onset latency, quality of sleep, number of awakenings, tolerance, adverse effects, and daytime alertness.
It is vital for you to read the medication guide after you order Ambien online. Before taking the medication, read the following instructions:
- Take Ambien precisely as prescribed by your doctor.
- Take only one tablet per night. Taking more than one dose a day can have adverse effects.
- Avoid drinking alcohol while on the medication of Ambien. Never consume Ambien if you had alcohol late in the evening or at night.
- Do not take Ambien right after dinner. The medicine will help you sleep much faster if you take it on an empty stomach.
- If Ambien does not treat your insomnia or worsen it after seven days of the administration, stop taking it and talk to your prescribing doctor about its effects.
- Get emergency treatment immediately in case of intentional or unintentional Ambien overdose.
- Take Ambien oral tablet by mouth. For a sublingual tablet, place it inside your tongue and let it sit until the tablet completely absorbs.
Side Effects of Ambien :
Some potential side effects of Ambien include:
- Back pain
- Dry mouth
- Feeling drugged
- Sore throat
- Heart palpitations