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Generic Name: Codeine
Brand Name: Nalex AC, BroveX CB, BroveX CBX
Drug Category: Opioid (narcotic)
- Codeine is a generic medication and a part of a group of drugs known as opioids, also famous as narcotics. They interact with opioid receptors in the human brain and elicit a range of responses within the body, from feelings of pain relief to relaxation and pleasure.
- Pierre Jean Robiquet discovered this opioid medication in 1832. Codeine is the most effective and safest medication needed in a health system, according to the World Health Organization list of essential medicines.
- The United States’ Drug Enforcement Administration has classified it as a schedule II-controlled drug substance.
Each Codeine tablet contains some inactive ingredients which may be active in suitable conditions. Inactive ingredients can include microcrystalline cellulose, colloidal silicon dioxide, stearic acid, and pregelatinized starch, etc.
Many people addicted to such opioid use street names for Codeine to hide their substance abuse. Drug abusers may use slang when talking with dealers or others who may have access to the drug. Some street names are Captain Cody, Cody, Schoolboy, Lean (when added to cough syrup medication), Doors and fours, Purple drank (when added to cough syrups), loads, and Pancakes, and syrup.
Using these secret words may allow people to conceal their addiction from their family members. However, hiding Codeine abuse can lead to long-term health problems.
What is Codeine used for?
This narcotic pain killer is a high-potent medication and a common drug of abuse. Due to its potential for abuse and habit-forming properties, Codeine approved for limited medical purposes only. Codeine is an opioid substance prescribed for the management of the following.
- Severe Pain (when combined with paracetamol and aspirin)
- Mild to moderate pain.
- Dry irritating cough and diarrhea.
People can Buy Codeine online in combination with decongestants and antihistamines for the treatment of cold and flu. When recommended by a doctor, people can use Codeine also for other medical purposes not given in this drug guide.
Some people use this medication recreationally for non-medical uses or to get high, by intentionally taking more than the recommended dose.
Mechanism of Action:
Codeine is an opioid pain-relieving substance that acts on the central nervous system to have an analgesic effect. Codeine produces morphine, which is ten times more potent agonist of the mu receptor. Opioid receptors are G-protein coupled receptors that negatively and positively regulate synaptic transmission through downstream signaling.
What are the typical doses of Codeine?
The selection of individuals for treatment with this opioid should be governed by the same principles that apply to the use of other similar opioid analgesics. Doctors should individualize therapy in every case, using non-opioid painkillers, opioids on a needed basis and combination medicines, and long-term opioid therapy in a progressive plan of pain relief.
While initiating the treatment, doctors should give special attention to the following:
- Physical and psychological conditions of an individual
- Drug potency, the total daily dose, and specific characteristics of the opioid the user has been taking previously.
- Type of pain and severity as well.
- The individuals’ degree of opioid tolerance.
Usual Adult dose for Pain:
People can initiate their treatment with 15 to 60 mg codeine orally up to every four hours as needed. They may increase their dosage at regular intervals, as indicated by their doctor. The maximum dose for 24 hours is 360 mg.
Higher amounts of drugs have not been shown to improve pain relief and are associated with an increased risk of side effects.
Are there any Adverse effects of using Codeine?
This medicine can cause severe and mild unwanted effects. However, these unpleasant effects do not occur as usual but may in some unsuitable conditions. The severity of adverse effects can depend on the user’s physical and mental health. Adverse effects can vary due to different situations, including.
Drug withdrawal symptoms can occur when a user stops using Codeine suddenly after long-term use. Withdrawal symptoms can include feeling anxious, trouble sleeping, teary eyes, runny nose, yawning, muscle aches, sweating, and a faster heartbeat.
Later symptoms may include nausea and vomiting, diarrhea, loss of appetite, stomach cramps, and enlarged pupils.
Using opioids through more frequent doses or in a more significant amount than prescribed can cause overdose symptoms and can include; bluish lips or skin chest pain or discomfort, unusual drowsiness. Decreased awareness and responsiveness, extreme sleepiness, slow or irregular heartbeat.
There is a risk of unexpected symptoms during therapy with Codeine. They can occur by chance even when using medicine properly.
Unknown effects can include confusion, bloating, blurred vision, cold, clammy skin, constipation, troubled, fast, slow or irregular breathing, troublesome breathing, no blood pressure or pulse, pale or blue lips, fingernails or skin.
As already mentioned, Codeine is a controlled substance, available on a prescription only. Patients can buy Codeine from online pharmacies and street pharmacies as well. If you are looking for Codeine without any prescription, it will be best to purchase it online. There are several online pharmacies offering Codeine with a free prescription label.
Buy Codeine Online roadside vendors may be dangerous as they can give you a duplicate or a fake product.
Difference between Codeine and Oxycodone?
There are individual differences and similarities when comparing oxycodone with Codeine. The primary and significant differences between Codeine and oxycodone –
The first key difference in Codeine compared to oxycodone is the fact that Codeine is a less potent drug. Codeine can be prescribed to manage moderate Pain, while oxycodone is a highly potent opioid reserved for mild to moderately severe pain. Additionally, Codeine also has less potential for abuse and addiction as compared to another opioid oxycodone.
Another significant difference in Codeine vs. oxycodone is that oxycodone is available as an extended-release tablet, although this is intended only for individuals who already have an opioid tolerance.