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Drug Introduction :
Suboxone is a medication approved by the U.S. FDA for the management of opiate dependence, including heroin addiction. The medical experts refer to it as the best medicine because it is a very “sticky” drug, which means it binds well with the same receptors as an opioid.
It is a prescription medication that combines buprenorphine and naloxone. Buprenorphine is in a group of medications called partial opioid agonists, which relieves the symptoms of opiate withdrawal. Naloxone relates to a class of medications called opioid antagonists, which reverse the effects of narcotics.
Suboxone contains certain inactive ingredients including lactose, cornstarch, citric acid, povidone K30, mannitol sodium citrate, magnesium stearate, and FD&C Yellow No. 6.
Licit Uses :
This medication is commonly used as part of a treatment program that typically includes lifestyle changes, counseling, and other interventions. Suboxone not only serves to reduce opioid cravings but also helps to suppress the symptoms of withdrawal. Ultimately, this medication is used in medical settings to help narcotic addicts stop taking opioids, get through treatment, and then remain in recovery. People can buy Suboxone online for the sole purpose – treating opioid addiction.
Illicit Uses :
The heroin and opioid crisis have killed more people in the United States than the Vietnam War. Narcotic abuse and addiction have reached epidemic proportions and are whole devastating communities all over the world. This medication has helped thousands of drug addicts abstain from using opioids and heroin. But Suboxone has a dark side as well and can be used for non-medical purposes.
Users who are prescribed this medication may use far more of the drug than prescribed to get an opiate high. Sometimes, people abuse it recreationally if they get it from a dealer or a friend.
Suboxone contains naloxone HCl dihydrate, an opioid receptor antagonist, and buprenorphine HCl, a partial agonist at the mu-opioid receptor.
Buprenorphine HCI is a white crystalline powder, freely soluble in methanol, sparingly soluble in water, soluble in alcohol and practically insoluble in cyclohexane.
Naloxone hydrochloride dihydrate is a white – slightly off-white powder and freely soluble in water, soluble in alcohol, and practically in ether and toluene.
Suboxone tablet contains naloxone and buprenorphine as above mentioned. Both ingredients work in a particular way.
Buprenorphine acts as a pain-reducing alternative in the central nervous system after binding opioid receptors. It combines the mu-receptors with high affinity and produces the analgesic effects in the central nervous system.
Naloxone is an opioid antagonist, competes with the opioid molecules in the central nervous system to prevent them from binding to the opioid receptors.
Control status and Warnings :
Suboxone is an FDA controlled drug substance and approved for limited medical uses only. The United States’ Food and Drug Administration has categorized it as a schedule III-controlled drug substance. In the United States, Suboxone is a prescription medication and available only on a legal recommendation.
This medication is not approved for long-term use and may only be used for a short period of time because adequate evidence of effectiveness for more prolonged use has not established.
Abuse potential :
Buprenorphine can be abused just like other similar to other opioids, illicit, or legal. Use it through the minimum amount of drugs for the shortest period of time to reduce risks of abuse, misuse, or diversion.
Respiratory depression :
Suboxone can produce significant respiratory depression and death, especially when taken in combination with CNS depressants such as benzodiazepines. Several reports regarding coma and mortality associated with the concomitant use of benzodiazepines and buprenorphine involved misused by self-injection.
Central nervous system depression
Users taking such treatment in the presence of opioid analgesics, benzodiazepines, general anesthetics, other tranquilizers, hypnotic/sedative, or other depressants may exhibit increased CNS depression.
People can take Suboxone by mouth with or without food as directed by their doctor. They should not increase their dose or use this drug more often or for longer than prescribed. Overdose or more frequent doses will not treat someone any faster but can increase the risks of side effects.
The user’s daily drug amount should be based on his or her medical condition and response to treatment. This medication should only be used for less than three weeks unless directed by a doctor.
People should take it under a proper schedule and stop gradually when discontinuing the treatment.
Side effects of Suboxone :
Common side effects
- Headache, anxiety, insomnia, nausea
- Opioid withdrawal symptoms like body aches, rapid heart rate, and body aches
- Insomnia (trouble sleeping)
- Depression, constipation, weakness or fatigue
- Burning tongue
- Redness in the mouth, etc.